Sleep-wake cycle: its physiology and impact on health was independently created by the national sleep foundation and was supported by an unrestricted educational grant from takeda pharmaceuticals north america, inc.
Physiology of sleep assoc prof sinan canan [email protected] wwwsinancanannet. The basic sleep physiology of histamine has been discussed above with regard to narcolepsy drug development histamine exerts its actions in brain through histamine h1, h2, and h3 receptors.
Physiology of sleep assoc prof sinan canan [email protected] wwwsinancanannet reticular formation (reticular activating system) neuromodulator systems arousal, reward system motor systems, reward, cognition, endocrine control mood, satiety, body temperature, introversion. Sleep is divided into two broad types: non-rapid eye movement (non-rem or nrem) sleep and rapid eye movement (rem) sleep non-rem and rem sleep are so different that physiologists identify them as distinct behavioral states non-rem sleep occurs first and after a transitional period is called slow-wave sleep or deep sleep. – however, only about 2% of all patients presenting to a sleep center have this diagnosis (zorick et al 1982) – this should not be confused with insomnia.
Due to this feature of rem sleep, it is often also referred to as paradoxical sleep as it is a paradox that one can be asleep and yet the brain is incredibly active non-rem sleep in contrast, non-rem sleep is characterised by deep sleep the duration of rem sleep episodes is longer earlier in the night when one is most tired. Physiology in sleep provides the physiological definition of sleep and presents the philosophical approach to sleep that departs from pharmacological and neurophysiological theories of sleep this book discusses the effects of sleep on cardiovascular and respiratory function, cerebral metabolism and blood flow, as well as temperature regulation.
The physiology of sleep sleep influences all of the body’s major physiologic systems, including thermoregulatory, musculoskeletal, endocrine, respiratory, cardiovascular, gastrointestinal, and immune systems sleep also impacts individual’s weight, mental health, and overall quality of life.